Moricin-1, Moricin-2

CAMPSQ1090

Title :

GenInfo Identifier :

20138941, 1246017

Source :

Bombyx mori [Silk moth]

Taxonomy :

Animalia, Insects

UniProt:

P82818, O96059

PDB:

1KV4

PubMed :

8530391

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E. coli JM109 ( MIC = 0.31 microM) , Acinetobacter sp. NISL B-4653 ( MIC = 0.27 microM) , Pseudomonas fluorescens IAM1179 ( MIC = 0.53 microM) , Pseudomonas aeruginosa IAM15140 ( MIC = 0.81 microM) , Bacillus subtilis IAM1107 ( MIC = 0.19 microM) , Bacillus megaterium IAM1030 ( MIC = 0.09 microM) , B. cereus IFO3457 ( MIC = 0.38 microM) , S. aureus ATCC6538P ( MIC = 0.21 microM) , S. aureus ATCC6538P ( MIC = 0.22 microM) , S. aureus IFO3083 ( MIC = 0.46 microM) , Staphylococcus xylosus IAM1312 ( MIC = 0.27 microM) , Staphylococcus epidermidis IFO12993 ( MIC = 0.18 microM) , S. pyogenes ATCC21547 ( MIC = 0.25 microM)

Validated :

Experimentally Validated

Pfam :

PF06451 : ( Moricin )

InterPro :

IPR009456 : Moricin_fam.

AMP Family :

Moricin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPMorP	Pattern	K-x-[GNP]-[AGIV]-x-[AI]-I-K-x(1,2)-G-x(1,3)-G-x-[AGILV]-x(2)-[AGIV]-[GI]-[NST]-[AGI]-x-[EGQS]-[TV]-x(2)-[DH]-[IV]-x-[ENS]	Variable
CAMPMorH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0045087	Biological Process	Innate immune response	IEA
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0045087	Biological Process	Innate immune response	IEA

Sequence:

AKIPIKAIKTVGKAVGKGLRAINIASTANDVFNFLKPKKRKH