Enterocin P precursor

CAMPSQ298

Title :

GenInfo Identifier :

2612870

Source :

Enterococcus faecium

Taxonomy :

Bacteria

UniProt:

O30434

PubMed :

9361419

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve

Target :

L.curvatus ( MIC = 17 ng/ml), L.fermentum ( MIC = 1 ng/ml), L.sake ( MIC = 144 ng/ml), Pediococcus acidalactici ( MIC = 69 ng/ml), P.pntosaceus FBB61 ( MIC = 136 ng/ml), P.pntosaceus FBB63 ( MIC = 18 ng/ml), L.lactis BB24 ( MIC = 22 ng/ml), Enterococcus faecium ( MIC = 2 ng/ml), E. faecalis ( MIC = 238 ng/ml), Staphylococcus carnosus ( MIC = 139 ng/ml), Listeria innocua ( MIC = 395 ng/ml), Bacillus cereus ( MIC = 286 ng/ml), Clostridium sporogenes ( MIC = 4 ng/ml), C, tyrobutyricum 3, 5CT ( MIC = 559 ng/ml), C, tyrobutyricum 1754 ( MIC = 412 ng/ml), Propionibacteruim sp P4 ( MIC = 37 ng/ml), Propionibacteruim sp P6 ( MIC = 26 ng/ml), C.perfringes ( MIC = 4 ng/ml), C.botulinum ( MIC = 259 ng/ml), Listeria monocytogenes7973 ( MIC = 35 ng/ml), Listeria monocytogenes LI5sv1/2 ( MIC = 33 ng/ml), Listeria monocytogenes 5105 ( MIC = 18 ng/ml), Listeria monocytogenes L11sv4 ( MIC = 39 ng/ml), Listeria monocytogenes Scott A ( MIC = 125 ng/ml), St. aureus 137 ( MIC = 190 ng/ml), St. aureus 196E ( MIC = 407 ng/ml), St. aureus 349 ( MIC = 221 ng/ml), St. aureus 361 ( MIC = 294 ng/ml), St. aureus 472 ( MIC = 269 ng/ml)

Validated :

Experimentally Validated

Comment :

No inhibition detected against Lactobacillus acidophilus, L.bulgaricus, L.casei, L.helveticus, L.plantarum, L.reuteri, L.sake 148, L.salivarious, pedicoccus acidilactici 347, P.pentosaceus PCI, Leuconostoc cremoris, Lactococcus cremoris, L lac

Pfam :

PF01721 : ( Class II bacteriocin )

InterPro :

IPR002633 : Bacteriocin_IIa.
IPR023384 : Bacteriocin_IIa_CS.
IPR023388 : Bacteriocin_IIa_dom.

AMP Family :

Bacteriocin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBacH35	HMM		35

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IDA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0050830	Biological Process	Defense response to Gram-positive bacterium	IDA

Sequence:

ATRSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGMGH