Esculentin-1B precursor

CAMPSQ688

Title :

GenInfo Identifier :

729445

Source :

Rana esculenta [Edible frog]

Taxonomy :

Animalia, Amphibians

UniProt:

P40844

PubMed :

8163497

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E.coli D21 ( MIC = 0.2 microM), B megaterium BmII ( MIC = 0.1 microM), S. aureus cowan I ( MIC = 0.4 microM), P.aeruginosa ATCC15692 ( MIC = 0.7 microM), C.ablicans ( MIC = 0.5 microM), S.cerevisiae ( MIC = 0.9 microM)

Hemolytic Activity :

Red Blood Cells (>100 microM )

Validated :

Experimentally Validated

Pfam :

PF08023 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )

InterPro :

IPR012521 : Antimicrobial_frog_2.
IPR004275 : Brevinin.

AMP Family :

Esculentin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPEscH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0044179	Biological Process	Hemolysis in other organism	IEA

Sequence:

GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC