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ScanProsite
ScanProsite
This form allows you to scan proteins for matches against the
PROSITE collection of motifs
as well as against your own patterns.
Option 1 - Submit PROTEIN sequences to scan them against the PROSITE collection of motifs.
Option 2 - Submit MOTIFS to scan them against a PROTEIN sequence database.
Option 3 - Submit PROTEIN sequences and MOTIFS to scan them against each other.
STEP 1 - Submit PROTEIN sequences
[
help
]
Submit PROTEIN sequences (max. 10)
Examples
Submit a PROTEIN database (max. 16MB) for repeated scans (The data will be stored on our server for 1 month).
Supported input:
UniProtKB
accessions e.g.
P98073
or identifiers e.g.
ENTK_HUMAN
PDB
identifiers e.g.
4DGJ
Sequences in
FASTA format
If you already have a code for your database, enter the code:
Otherwise,
upload your database as a FASTA file to obtain a code
STEP 2 - Select options
[
help
]
Exclude motifs with a high probability of occurrence
from the scan
Exclude profiles
from the scan
Run the scan at high sensitivity
(show weak matches for profiles)
STEP 1 - Enter a MOTIF or a combination of MOTIFS
Examples
[
help
]
Supported input:
A PROSITE accession e.g.
PS50240
or identifier e.g.
TRYPSIN_DOM
Your own pattern e.g.
P-x(2)-G-E-S-G(2)-[AS]
A combination of PROSITE accessions/identifiers e.g.
PS50240 and PS50068
, e.g.
PS50240 and not ( PS00134 or PS00135 )
A combination of PROSITE accessions/identifiers and your own pattern e.g.
PS50240 and P-x(2)-G-E-S-G(2)-[AS]
» More
» Options
[
help
]
Mimimal number of hits per matched sequences
:
Profile option
Run the scan at a high sensitivity
(show weak matches for profiles)
Pattern options
Number of X characters in a scanned sequence that can be matched by a conserved position in a pattern:
Match mode
:
greedy, overlaps, no includes
greedy, overlaps, includes
greedy, no overlaps
not greedy, overlaps, no includes
not greedy, overlaps, includes
not greedy, no overlaps
STEP2 - Select a PROTEIN sequence database
[
help
]
UniProtKB
Swiss-Prot
Include splice variants
TrEMBL
PDB
Your protein database
If you already have a code for your database, enter the code:
Otherwise,
upload your database as a FASTA file to obtain a code
Randomized UniProtKB/Swiss-Prot
[
help
]
reversed
window20
Exclude fragments (concerns UniProtKB only)
» Filters
[
help
]
On length >= than:
On length <= than:
On taxonomy:
any taxonomical term e.g.
Homo sapiens
, e.g.
Fungi; Arthropoda
or corresponding
TaxID
e.g.
9606
, e.g.
4751; 6656
On description:
e.g.
protease
On Tissue expression (
Bgee
data):
Any (no filtering)
adrenal gland - interrenal gland
alimentary system
artery
blood
bone
brain
cartilage
central nervous system
cerebellum
ciliary body
dermis
diencephalon
dorsal root ganglion
endocrine system
epidermis
eye
gall bladder
gut
heart
heart endocardium
heart myocardium
hematopoietic system
hindbrain
hypophysis
inner ear
intestine
iris
joint
lens
liver
lung
medulla oblongata
midbrain
muscle
oesophagus
olfactory organ
optic II nerve
oral cavity
ovary
pancreas
peripheral nervous system
peritoneum
pharyngeal arch 1
pineal gland
renal system
reproductive system
respiratory system
retina
skin
spinal cord
spleen
swim bladder
testis
thymus
thyroid
vein
whole organism
(only on Human, Xenopus, Mouse and Zebrafish; adult stage)
N.B. Does not consider splice variants of UniProtKB/Swiss-Prot.
STEP 1 - Submit PROTEIN sequences
[
help
]
Submit PROTEIN sequences (max. 1'000)
Examples
Submit a PROTEIN database (max. 16MB) for repeated scans (The data will be stored on our server for 1 month).
Supported input:
UniProtKB
accessions e.g.
P98073
or identifiers e.g.
ENTK_HUMAN
PDB
identifiers e.g.
4DGJ
Sequences in
FASTA format
If you already have a code for your database, enter the code:
Otherwise,
upload your database as a FASTA file to obtain a code
STEP 2 - Enter a MOTIF or a combination of MOTIFS
Examples
[
help
]
Supported input:
A PROSITE accession e.g.
PS50240
or identifier e.g.
TRYPSIN_DOM
Your own pattern e.g.
P-x(2)-G-E-S-G(2)-[AS]
A combination of PROSITE accessions/identifiers e.g.
PS50240 and PS50068
, e.g.
PS50240 and not ( PS00134 or PS00135 )
A combination of PROSITE accessions/identifiers and your own pattern e.g.
PS50240 and P-x(2)-G-E-S-G(2)-[AS]
» More
» Options
[
help
]
Profile option
Run the scan at a high sensitivity
(show weak matches for profiles)
Pattern options
Number of X characters in a scanned sequence that can be matched by a conserved position in a pattern:
Match mode
:
greedy, overlaps, no includes
greedy, overlaps, includes
greedy, no overlaps
not greedy, overlaps, no includes
not greedy, overlaps, includes
not greedy, no overlaps
STEP 3 - Select output options and submit your job
Output format
:
Graphical view
Simple view
Text
FASTA
Table
Matchlist
Maximum number of displayed matches
:
1'000
10'000
100'000 (by email only)
If you select 100'000, results are returned by email and not all output formats are available.
Retrieve complete sequences
:
If you choose this option, not all output formats are available.
Receive your results by email
Email
:
Note that not all output formats are available for results returned by email.
Job title
:
If available, the job title will be included in the subject of the results email.