Tachystatin-B2

CAMPSQ1074

Title :

Tachystatin-B2

GenInfo Identifier :

150387845

Source :

Tachypleus tridentatus [Japanese horseshoe crab]

Taxonomy :

Animalia

UniProt:

P0C1Z9

PDB:

2DCW

Structure Database :

CAMPST112

PubMed :

10473569

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve

Target :

S.aureus ( IC50 = 7.4 microg/ml) , C.albicans (IC 50 = 3.0 microg/ml) , P.pastoris ( IC50 = 0.1 microg/ml)

Validated :

Experimentally Validated

Comment :

Inactive against E. coli ( IC50 = 100 microg/ml )

Pfam :

PF11478 : ( Antimicrobial chitin binding protein tachystatin B )

InterPro :

IPR020957 : Tachystatin_B.

AMP Family :

Tachystatin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPTacH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0050832	Biological Process	Defense response to fungus	IEA
GO:0031640	Biological Process	Killing of cells of other organism	IEA

Sequence:

YITCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF