Myeloid antimicrobial peptide BMAP-27

CAMPSQ114

Title :

GenInfo Identifier :

1296456

Source :

Bos taurus [Bovine]

Taxonomy :

Animalia, Mammals

UniProt:

P54228

PDB:

2KET

Structure Database :

CAMPST173

PubMed :

8910461

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

E. coli ATCC 25922 ( MIC = 2 microM ), E. coli ML35 ( MIC =4 microM ), E. coli D21 ( MIC = 4 microM ), S. typhimurium ATCC 14028 ( MIC = 4 microM ), P. aeruginosa ATCC 27853 ( MIC = 1 microM ), S. marcescens ATCC 8100 ( MIC = 2 microM ), S. aureus ATCC 25923 ( MIC = 2 microM ), S. aureus Cowan 1 ( MIC = 2 microM ), S. aureus MRSA ( MIC = 4 microM ), S. epidermidis ATCC 12228 ( MIC = 1 microM ), B. megaterium Bm11 ( MIC = 2 microM ), C. albicans ( MIC = 16 microM ), C. neoformans ( MIC = 4 microM )

Validated :

Experimentally Validated

Pfam :

PF00666 : ( Cathelicidin )

InterPro :

IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.

AMP Family :

Cathelicidin

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0050832	Biological Process	Defense response to fungus	IEA
GO:0031640	Biological Process	Killing of cells of other organism	IEA

Sequence:

GRFKRFRKKFKKLFKKLS