Melittin

CAMPSQ1142

Title :

Melittin

Source :

Apis mellifera [Honeybee]

Taxonomy :

Animalia, Insects

NCBI Taxonomy :

7460

UniProt:

PDB:

1BH1, 2MLT

PubMed :

Length :

26

Activity :

Antibacterial, Antiviral

Gram Nature :

Gram-ve

Target :

E. coli (1.5 microM) , HIV (0.9?1.5 microM)

Hemolytic Activity :

sheep red blood cells (11mM)

Validated :

Experimentally Validated

Pfam :

PF01372 : ( Melittin )

InterPro :

IPR002116 : Melittin/Api_allergen.

AMP Family :

Melittin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPMelH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0016021	Cellular Component	Integral to membrane	IEA
GO:0044218	Cellular Component	Other organism cell membrane	IEA
GO:0004860	Molecular Function	Protein kinase inhibitor activity	IEA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0044179	Biological Process	Hemolysis in other organism	IEA
GO:0006811	Biological Process	Ion transport	IEA
GO:0006469	Biological Process	Negative regulation of protein kinase activity	IEA

Sequence:

GIGAVLKVLTTGLPALISWIKRKRQQ