Rugosin-A

CAMPSQ264

Title :

Rugosin-A

GenInfo Identifier :

2493347

Source :

Rana rugosa [Japanese wrinkled frog]

Taxonomy :

Animalia, Amphibians

UniProt:

P80954

PubMed :

7612013

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

Staphylococcus aureus 209P ( MIC = 6.25 microg/ml), Bacillus subtilis ATCC6633 ( MIC = 12.5 microg/ml), Micrococcus luteus ATCC9341 ( MIC = 25 microg/ml), Streptococcus pyogenes COOK ( MIC = 50 microg/ml), Eschericia coli NIHJ ( MIC = 100 microg/ml), Pseudomonas aeruginosa PAO-1 ( MIC = >100 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF08023 : ( Frog antimicrobial peptide )

InterPro :

IPR012521 : Antimicrobial_frog_2.

AMP Family :

Rugosin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPRugP	Pattern	K-[ADQT]-x-A-x(2)-[ILV]-[AG]-K-x(4,5)-G-[AIV]-x(2)-[AGT]-[ALV]	Variable
CAMPRugH	HMM		Variable
CAMPBreH29	HMM		29

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

GLLNTFKDWAISIAKGAGKGVLTTLSCKLDKSC