| CAMPSQ2640 |
| Title : |
Temporin-SHf precursor, partial |
| GenInfo Identifier : |
295004058 |
| Source : |
Pelophylax saharicus [Sahara frog] |
| Taxonomy : |
Animalia, Amphibians |
| NCBI Taxonomy : |
70019 |
| UniProt: |
D4YWD1 |
| PubMed : |
20308076 |
| Length : |
9 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram+ve, Gram-ve |
| Target : |
E. coli ATCC 25922 (MIC = 25 microM), E. coli ATCC 35218 (MIC >200 microM), E. coli D21 (MIC = 100 microM), E. coli ML-35p (MIC = 30 microM), P. aeruginosa ATCC 27853 (MIC >200 microM), S. aureus ATCC 25923 (MIC = 12.5 microM), E. faecalis ATCC 29212 (MIC = 50 microM), B. megaterium (MIC = 3 microM), C. albicans ATCC 90028 (MIC=50 microM), C. parapsilosis ATCC 22019 (MIC=50 microM), S. cerevisiae (MIC=12.5 microM), A. flavus (MIC>200 microM) |
| Hemolytic Activity : |
Present but temporin-SHf is not cytotoxic against human erythrocytes (LC50 = 200 μm), with a hemolytic activity detected only at peptide concentration far above the MIC values determined for the sensitive strains (3 €“50 μm) |
| Validated : |
Experimentally Validated |
| Comment : |
Also Anti-Protozoan |
| Pfam : |
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
|
| InterPro : |
IPR004275 : Brevinin.
|
| AMP Family : |
Temporin |
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
IEA |
| GO:0042742 |
Biological Process |
Defense response to bacterium |
IEA |
|
Sequence: |
FFLSRIFGK |
