CAMPSQ2671
Title : Phylloseptin-1 precursor
GenInfo Identifier : 311334887
Source : Phyllomedusa sauvagii [Sauvage leaf frog]
Taxonomy : Animalia, Amphibians
UniProt: E3PQH3
PubMed : 20451254
Length : 18
Activity : Antibacterial
Gram Nature : Gram+ve
Target : Staphylococcus aureus [ MIC = 5 microM ], Staphylococcus aureus [ Minimal biofilm eradication concentration (MBEC) = 5 microM ]
Hemolytic Activity : At the MIC/MBEC for S. aureus (5 μM €”indicated by an arrow) the peptide displayed just 6.7% lysis of red blood cells using a standardised assay procedure. Standard errors were typically <0.2% of mean values throughout.
Validated : Experimentally Validated
Pfam : PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR004275 : Brevinin.
AMP Family : Phylloseptin
Signature :
ID Type Pattern / HMM T. Length
CAMPPhyP Pattern L-[GS]-[LM]-[IL]-P-x(1,2)-I-x(1,3)-S-[AGT]-[AILV]-[ASV] Variable
CAMPPhyH HMM Variable
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IEA
GO:0042742 Biological Process Defense response to bacterium IEA
Sequence:
LSLIPHIVSGVASIAKHF