| CAMPSQ2671 |
| Title : |
Phylloseptin-1 precursor |
| GenInfo Identifier : |
311334887 |
| Source : |
Phyllomedusa sauvagii [Sauvage leaf frog] |
| Taxonomy : |
Animalia, Amphibians |
| NCBI Taxonomy : |
8395 |
| UniProt: |
E3PQH3 |
| PubMed : |
20451254 |
| Length : |
18 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram+ve |
| Target : |
Staphylococcus aureus [ MIC = 5 microM ], Staphylococcus aureus [ Minimal biofilm eradication concentration (MBEC) = 5 microM ] |
| Hemolytic Activity : |
At the MIC/MBEC for S. aureus (5 μM €”indicated by an arrow) the peptide displayed just 6.7% lysis of red blood cells using a standardised assay procedure. Standard errors were typically <0.2% of mean values throughout. |
| Validated : |
Experimentally Validated |
| Pfam : |
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
|
| InterPro : |
IPR004275 : Brevinin.
|
| AMP Family : |
Phylloseptin |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPPhyP |
Pattern |
L-[GS]-[LM]-[IL]-P-x(1,2)-I-x(1,3)-S-[AGT]-[AILV]-[ASV] |
Variable |
|
CAMPPhyH |
HMM |
 |
Variable |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
IEA |
| GO:0042742 |
Biological Process |
Defense response to bacterium |
IEA |
|
Sequence: |
LSLIPHIVSGVASIAKHF |
