Gaegurin-4

CAMPSQ282

Title :

Gaegurin-4

GenInfo Identifier :

2506236

Source :

Rana rugosa [Japanese wrinkled frog]

Taxonomy :

Animalia, Amphibians

UniProt:

P80398

PDB:

2G9L

Structure Database :

CAMPST124

PubMed :

7999137

Length :

Activity :

Antibacterial, Antifungal, Antiparasitic

Gram Nature :

Gram+ve, Gram-ve

Target :

Micrococcus luteus ( MIC = 2.5 microg/ml), Staphylococcus epidermidis ( MIC = 10 microg/ml), Bacillus subtilis ( MIC = 10 microg/ml), Klebsiella pneumoniae ( MIC = 25 microg/ml), Shigella dysentariae ( MIC = 25 microg/ml), Pseudomonas putida ( MIC = 100 microg/ml), Pseudomonas aeruginosa ( MIC = 100 microg/ml), Eshchericia coli ( MIC = 75 microg/ml), Saccharomyces cerevisiae ( MIC = 200 microg/ml), Candida albicans ( MIC = 200 microg/ml), Salmonella typhimurium ( MIC = 200 microg/ml), Proteus mirabilis ( MIC = >200 microg/ml), Serratia marcescens ( MIC = >200 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF08023 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )

InterPro :

IPR012521 : Antimicrobial_frog_2.
IPR004275 : Brevinin.
IPR018247 : EF_Hand_1_Ca_BS.

AMP Family :

Gaegurin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPRugP	Pattern	K-[ADQT]-x-A-x(2)-[ILV]-[AG]-K-x(4,5)-G-[AIV]-x(2)-[AGT]-[ALV]	Variable
CAMPGaeH	HMM		Variable
CAMPRanH28	HMM		28

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

GILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC