Sakacin P

CAMPSQ310

Title :

Sakacin P

GenInfo Identifier :

2735690

Source :

Lactobacillus sakei

Taxonomy :

Bacteria

UniProt:

P35618

PDB:

1OG7, 1OHM, 1OHN

Structure Database :

CAMPST48, CAMPST49, CAMPST50

PubMed :

8636023

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve

Target :

Enterococcus faecalis LMG2708 ( IC50 = 8.8 ng/ml ), Lactobacillus LMG2003 ( IC50 = 35 ng/ml ), L.coryniformis LMG2308 ( IC50 = 5.8 ng/ml ), L.sake LMG2313 ( IC50 = 5.8 ng/ml ), L.sake LTH673 BAC+ ( IC50 = >1200 ng/ml ), L.sake LTH 673 Bac- ( IC50 = 57 ng/ml ), Pedidcoccus pentosaceus LMG2722 ( IC50 = 2500 ng/ml )

Validated :

Experimentally Validated

Comment :

Inactive against L.plantarum LMG2375, L.sake LMG2376, Pedidcoccus pentosaceus LMG 2319

Pfam :

PF01721 : ( Class II bacteriocin )

InterPro :

IPR002633 : Bacteriocin_IIa.
IPR023384 : Bacteriocin_IIa_CS.
IPR023388 : Bacteriocin_IIa_dom.

AMP Family :

Bacteriocin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBacH35	HMM		35
CAMPBacH30	HMM		30

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

KYYGNGVHCGKHSCTVDW