| CAMPSQ3118 |
| Title : |
Ascaphin-8 |
| Source : |
Ascaphus truei [Coastal tailed frog] |
| Taxonomy : |
Animalia, Amphibians |
| UniProt: |
P0CJ32 |
| PubMed : |
15207717 |
| Length : |
19 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram+ve, Gram-ve |
| Target : |
Escherichia coli ( MIC = 6 microM ), Staphylococcus aureus ( MIC = 6 microM ), Pseudomonas aeruginosa ( MIC = 50 microM ), Enterobacter cloacae ( MIC = 13 microM ), Klebsiella pneumoniae ( MIC = 25 microM ), Proteus mirabilis ( MIC > 100 microM ), S. epidermidis ( MIC =25 microM ), E. faecalis ( MIC > 100 microM ), Streptococcus Group B ( MIC = 13 microM ), C. albicans ( MIC = 100 microM ) |
| Hemolytic Activity : |
Human erythrocytes ( HC50 = 50 microM ) |
| Validated : |
Experimentally Validated |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPAscP |
Pattern |
G-F-[KR]-D-x-[IL]-K-G-A-A-K-x-[FL]-[IV]-K-T-V-[AL] |
Variable |
|
CAMPAscH |
HMM |
 |
Variable |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
IDA |
| GO:0019835 |
Biological Process |
Cytolysis |
IEA |
| GO:0050829 |
Biological Process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological Process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0044179 |
Biological Process |
Hemolysis in other organism |
IDA |
|
Sequence: |
GFKDLLKGAAKALVKTVLF |
