CAMPSQ3316
Title : Cathelicidin, EA-CATH1
GenInfo Identifier : 225579557
Source : Equus asinus [Donkey]
Taxonomy : Animalia, Mammals
UniProt: C1K8V9
PubMed : 20423460
Length : 25
Activity : Antibacterial
Gram Nature : Gram-ve
Target : Staphylococcus aureus (IS) (MIC = 1.2 microg/ml), Staphylococcus aureus ATCC2592 (MIC = 0.6 microg/ml), Staphylococcus haemolyticus (092401) (IS, DRa) (MIC = 0.6 microg/ml), Nocardia asteroids (IS) (MIC = 1.2 microg/ml), Enterococcus faecium (IS091299) (MIC = 9.4 microg/ml), Propionibacterium acnes ATCC11827 (MIC = 4.7 microg/ml), Klebsiella oxytoca (IS) (MIC = > 100 microg/ml), Aeromonas sobria (IS) (MIC = 9.4 microg/ml), Acinetobacter baumannii 092178 (IS, DRb) (MIC = 4.7 microg/ml), Acinetobacter baumannii 092373 (IS) (MIC = 9.4 microg/ml), Stenotrophomonas maltophilia (IS) (MIC = 9.4 microg/ml), Pseudomonas aeruginosa ATCC27853 (MIC = > 100 microg/ml), Pseudomonas aeruginosa 091411(IS) (MIC = 18.8 microg/ml), Pseudomonas aeruginosa 091412 (IS) (MIC = > 100 microg/ml), Pseudomonas aeruginosa 091413 (IS) (MIC = > 100 microg/ml), Escherichia coli 091335 (IS) (MIC = 75 microg/ml), Klebsiella pneumoniae 091372 (IS) (MIC = > 100 microg/ml), Klebsiella pneumoniae 091373 (IS) (MIC = > 100 microg/ml), Proteus vulgaris (IS) (MIC = > 100 microg/ml), Proteus mirabilis (IS) (MIC = > 100 microg/ml), Candida albicans 092251 (IS) (MIC = 9.4 microg/ml), Candida albicans ATCC2002 (MIC = 9.4 microg/ml), Slime mould (MIC = 4.7 microg/ml), Candida glabrata 090902 (IS) (MIC = > 100 microg/ml), Candida tropicalis 092422 (IS) (MIC = > 100 microg/ml),
Validated : Experimentally Validated
Comment : These organisms did not show activity at a dose of 2mg/ml: Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS)
Pfam : PF00666 : ( Cathelicidin )
AMP Family : Cathelicidin
Signature :
ID Type Pattern / HMM T. Length
CAMPCatH HMM Variable
Sequence:
 KRRGSVTTRYQFLMIHLLRPKKLFA