Brevinin-1-AJ1 antimicrobial peptide precursor

CAMPSQ4041

Title :

GenInfo Identifier :

425872776

Source :

Amolops jingdongensis [Chinese torrent frog]

Taxonomy :

Animalia, Amphibians

NCBI Taxonomy :

1077530

UniProt:

K7Z430

PubMed :

22828809

Length :

Activity :

Antibacterial, Antifungal

Target :

E. coli ATCC 25922 ( MIC=18.75 microg/ml ), B. dysenteriae ( MIC=9.38 microg/ml ), S. aureus ATCC 2592 ( MIC=1.17 microg/ml ), B. subtilis ATCC 6633 ( MIC=4.7 microg/ml ), C. albicans ATCC 2002 ( MIC=4.7 microg/ml )

Hemolytic Activity :

Rabbit erythrocytes 7.62% lysis (25 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF08018 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )

InterPro :

IPR012520 : Antimicrobial_frog_1.
IPR004275 : Brevinin.

AMP Family :

Brevinin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBreH23	HMM		23

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

FLSTLLKVAFKVVPTLFCPITKKC