CAMPSQ4332
Title : Ascaphin-1
Source : Ascaphus truei [Coastal tailed frog]
Taxonomy : Animalia, Amphibians
UniProt: P0CJ25
PubMed : 15207717
Length : 23
Activity : Antibacterial, Antifungal
Gram Nature : Gram+ve, Gram-ve
Target : Escherichia coli ( MIC = 25 microM ), Staphylococcus aureus ( MIC > 100 microM ), Pseudomonas aeruginosa ( MIC > 100 microM ), Enterobacter cloacae ( MIC = 50 microM ), Klebsiella pneumoniae ( MIC = 50 microM ), Proteus mirabilis ( MIC > 100 microM ), S. epidermidis ( MIC > 100 microM ), E. faecalis ( MIC > 100 microM ), Streptococcus Group B ( MIC = 100 microM ), C. albicans ( MIC > 100 microM )
Hemolytic Activity : Human erythrocytes ( HC50 > 200 microM )
Validated : Experimentally Validated
Signature :
ID Type Pattern / HMM T. Length
CAMPAscP Pattern G-F-[KR]-D-x-[IL]-K-G-A-A-K-x-[FL]-[IV]-K-T-V-[AL] Variable
CAMPAscH HMM Variable
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IDA
GO:0050829 Biological Process Defense response to Gram-negative bacterium IDA
Sequence:
GFRDVLKGAAKAFVKTVAGHIAN