CAMPSQ4332 |
Title : |
Ascaphin-1 |
Source : |
Ascaphus truei [Coastal tailed frog] |
Taxonomy : |
Animalia, Amphibians |
UniProt: |
P0CJ25 |
PubMed : |
15207717 |
Length : |
23 |
Activity : |
Antibacterial, Antifungal |
Gram Nature : |
Gram+ve, Gram-ve |
Target : |
Escherichia coli ( MIC = 25 microM ), Staphylococcus aureus ( MIC > 100 microM ), Pseudomonas aeruginosa ( MIC > 100 microM ), Enterobacter cloacae ( MIC = 50 microM ), Klebsiella pneumoniae ( MIC = 50 microM ), Proteus mirabilis ( MIC > 100 microM ), S. epidermidis ( MIC > 100 microM ), E. faecalis ( MIC > 100 microM ), Streptococcus Group B ( MIC = 100 microM ), C. albicans ( MIC > 100 microM ) |
Hemolytic Activity : |
Human erythrocytes ( HC50 > 200 microM ) |
Validated : |
Experimentally Validated |
Signature : |
ID |
Type |
Pattern / HMM |
T. Length |
CAMPAscP |
Pattern |
G-F-[KR]-D-x-[IL]-K-G-A-A-K-x-[FL]-[IV]-K-T-V-[AL] |
Variable |
CAMPAscH |
HMM |
|
Variable |
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular Component |
Extracellular region |
IDA |
GO:0050829 |
Biological Process |
Defense response to Gram-negative bacterium |
IDA |
|
Sequence: |
GFRDVLKGAAKAFVKTVAGHIAN |