Human beta-defensin-2 WT hBD

CAMPSQ486

Title :

Human beta-defensin-2 WT hBD - 2

GenInfo Identifier :

4826692

Source :

Homo sapiens [Human]

Taxonomy :

Animalia, Mammals

UniProt:

O15263

PDB:

1E4Q, 1FD3, 1FD4, 1FQQ

Structure Database :

CAMPST498, CAMPST20, CAMPST21, CAMPST508

PubMed :

9727055

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E.coli D31( MIC = 62 microg/ml ),E.coli ATCC ( MIC = 62 microg/ml ), Pseudomonas aeruginosa ATCC ( MIC = 62 microg/ml ), Staphylococcus aureus ATCC ( MIC = 62 microg/ml ) , E. faecalis ATCC ( MIC = 15 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF00711 : ( Beta defensin )

InterPro :

IPR001855 : Defensin_beta-typ.
IPR006080 : Defensin_beta/neutrophil.

AMP Family :

Defensin

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	TAS
GO:0005796	Cellular Component	Golgi lumen	TAS
GO:0006935	Biological Process	Chemotaxis	TAS
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0007186	Biological Process	G-protein coupled receptor signaling pathway	TAS
GO:0045087	Biological Process	Innate immune response	TAS

Sequence:

GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP