Beta-defensin-3

CAMPSQ657

Title :

Beta-defensin-3

GenInfo Identifier :

9756284

Source :

Homo sapiens [Human]

Taxonomy :

Animalia, Mammals

NCBI Taxonomy :

9606

UniProt:

P81534

PDB:

1KJ6

Structure Database :

CAMPST33

PubMed :

11085990

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

S. aureus ( MIC = 2.5 microg/ml), Streptococcus pyogenes, P. aeruginosa, E. coli, Candida albicans, Enterococcus faecium

Hemolytic Activity :

No Hemolytic activity

Validated :

Experimentally Validated

Pfam :

PF00711 : ( Beta defensin )

InterPro :

IPR001855 : Defensin_beta-typ.

AMP Family :

Defensin

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	NAS
GO:0005796	Cellular Component	Golgi lumen	TAS
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0045087	Biological Process	Innate immune response	TAS
GO:0006965	Biological Process	Positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	TAS

Sequence:

GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK