Antimicrobial protein CAP18 precursor

CAMPSQ73

Title :

GenInfo Identifier :

117149

Source :

Oryctolagus cuniculus [Rabbit]

Taxonomy :

Animalia, Mammals

UniProt:

P25230

PDB:

1LYP

Structure Database :

CAMPST640

PubMed :

8313956

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

Escherichia coli ML 35 (MIC = 2 microM), Escherichia coli ATCC 25922 (MIC = 4 microM), Salmonella typhimurium ATCC 14028 (MIC = 2 microM), Pseudomonas aeruginosa ATCC 27853 (MIC = 0.5 microM), Bacillus megaterium (MIC = 4 microM), Staphylococcus aureus ATCC 25923 (MIC = 4 microM)

Validated :

Experimentally Validated

Pfam :

PF12153 : ( LPS binding domain of CAP18 (C terminal) )
PF00666 : ( Cathelicidin )

InterPro :

IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
IPR022746 : Cathlecidin_C.

AMP Family :

Cathelicidin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPCatH	HMM		Variable
CAMPCatH37	HMM		37

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

GLRKRLRKFRNKIKEKLKKI