Cathelin-related peptide SC5

CAMPSQ877

Title :

GenInfo Identifier :

1710861

Source :

Ovis aries [Sheep]

Taxonomy :

Animalia, Mammals

UniProt:

P49928 , P49929

PDB:

1FRY

Structure Database :

CAMPST23

PubMed :

8549789

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

Staphylococcus aureus 25923 ( MIC = 5 - 10 microg/ml) , Pseudomonas aeruginosa 27853 ( MIC = 5 - 10 microg/ml), Klebsiella pneumoniae 13883 ( MIC = 2.5-5 microg/ml) , Candida albicans 14053 ( MIC = 10-25 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF00666 : ( Cathelicidin )

InterPro :

IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.

AMP Family :

Cathelicidin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPCatH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

RGLRRLGRKIAHGVKKYGPTVLRIIRIAG