Neutrophil cationic antibacterial polypeptide of 11 kDa

CAMPSQ898

Title :

GenInfo Identifier :

81867362

Source :

Cavia porcellus [Guinea pig]

Taxonomy :

Animalia, Mammals

NCBI Taxonomy :

10141

UniProt:

Q91X12

PubMed :

8644997

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E. coli ( ED50 = 30-35 nM ) , S.aureus ( ED50 = 90-120 nM )

Validated :

Experimentally Validated

Pfam :

PF00666 : ( Cathelicidin )

InterPro :

IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.

AMP Family :

Cathelicidin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPCatH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042581	Cellular Component	Specific granule	IEA
GO:0050829	Biological Process	Defense response to Gram-negative bacterium	IEA
GO:0050830	Biological Process	Defense response to Gram-positive bacterium	IEA
GO:0051873	Biological Process	Killing by host of symbiont cells	IEA
GO:0044130	Biological Process	Negative regulation of growth of symbiont in host	IEA
GO:0044140	Biological Process	Negative regulation of growth of symbiont on or near host surface	IEA

Sequence:

GLRKKFRKTRKRIQKLGRKIGKTGRKVWKAWREYGQIPYPCRI