Dermaseptin-01

CAMPSQ986

Title :

Dermaseptin-01

GenInfo Identifier :

41016983

Source :

Phyllomedusa oreades [Orange-legged leaf frog]

Taxonomy :

Animalia, Amphibians

NCBI Taxonomy :

239355

UniProt:

P83637

PubMed :

12379643

Length :

Activity :

Antibacterial, Antiparasitic

Gram Nature :

Gram+ve, Gram-ve

Target :

S. aureus ATCC 25923 ( MIC = 3.20 microM), P. aeruginosa ATCC 27853 ( MIC = 6.42 microM), E. coli ATCC 25922 ( MIC = 6.42 microM), A. calcoaceticus wt ( MIC = 25.67 microM), E. coli wt MR ( MIC = 6.42 microM), S. aureus MRSA ( MIC = 12.83 microM), T. cruz ( MIC = 1-4 microM)

Hemolytic Activity :

Human red blood cells (4-128 microg/mL)

Validated :

Experimentally Validated

Pfam :

PF12121 : ( Dermaseptin )

InterPro :

IPR022731 : Dermaseptin.

AMP Family :

Dermaseptin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPDerH	HMM		Variable
CAMPDerH25	HMM		25

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IDA
GO:0050829	Biological Process	Defense response to Gram-negative bacterium	IDA
GO:0050830	Biological Process	Defense response to Gram-positive bacterium	IDA

Sequence:

GLWSTIKQKGKEAAIAAAKAAGQAALGAL